PD-1 anticorps (Biotin)
Aperçu rapide pour PD-1 anticorps (Biotin) (ABIN7608071)
Antigène
Voir toutes PD-1 (PDCD1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Biotinylated Anti-Canine PD-1 antibody(4E1), Rabbit mAb
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Isotype
- IgG
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Indications d'application
- ELISA 1/5000-10000
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Date de péremption
- 12 months
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- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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Autre désignation
- PD-1
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Sujet
- Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells, it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
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NCBI Accession
- NP_001301026
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Pathways
- Cancer Immune Checkpoints
Antigène
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